The normal serum total bilirubin value for adults is 3.4~17.1 μmol/L. If the total bilirubin reaches 274 μmol/L, it is moderate jaundice, which can lead to hepatic insufficiency, and should be treated as soon as possible by consulting a doctor to clarify the cause of the disease. Bilirubin is produced by the breakdown and destruction of senescent red blood cells in the monocyte-macrophage system of the liver, spleen and bone marrow. Excessive destruction of red blood cells (hemolytic anemia), impaired bilirubin excretion, and biliary tract obstruction (e.g., hepatitis, bile duct inflammation, etc.) can cause bilirubin metabolism disorders, resulting in elevated serum bilirubin levels. Clinically, serum total bilirubin is often tested to determine the presence or absence of jaundice, the degree of jaundice, and to speculate on the etiology of jaundice. According to the total bilirubin level, jaundice can be categorized as follows: total bilirubin >17.1 µmol/L, <34. 2µmol/L for hidden jaundice; 34.2~171µmol/L for mild jaundice; 171~342µmol/L for moderate jaundice; >342µmol/L for high jaundice. If the total bilirubin level exceeds the normal range, it is necessary to go to the hospital as soon as possible for consultation and early formal treatment to avoid further deterioration of the condition.