Men staying up late once in a while does not usually cause infertility. If men stay up late for a long period of time, they will experience erectile dysfunction and abnormal sperm quality and quantity, which may affect female conception. If men stay up late once in a while, it will not affect the reproductive function, and usually will not affect female conception. If a man stays up late for a long time, it may lead to abnormal levels of estrogen and androgen in the body, which may lead to erectile dysfunction. This may lead to erectile dysfunction, in which the penis is not hard enough or the erection time is too short, which may affect the conception of the woman. In addition, men who stay up late for a long time may damage the sperm production function of the testicles, which will lead to a decline in sperm quality and sperm count, which will also reduce the chances of female conception. It is recommended that during the preparation for pregnancy, men need to develop regular sleep habits, avoid staying up late for a long time, should not smoke and drink alcohol, and can do appropriate physical exercise every day, such as jogging, jumping rope and so on.