Nose blocked, can not sleep at night may be sinusitis, allergic rhinitis, nasal septum deviation, nasal polyps and other causes, according to its cause, give medication, surgical treatment. 1. Sinusitis: sinusitis caused by inflammation of the nose, you can apply saline rinse nasal cavity, promote nasal secretion outflow, local application of fluticasone propionate nasal spray, furosemide nasal drops, etc., to improve the congestion of the nasal mucosa, if it is a bacterial infection, can be combined with oral cefaclor, cephradine, etc. to fight infection, to alleviate nasal congestion. 2. Allergic rhinitis: nasal mucosa causes allergic reaction leading to nasal congestion, oral cetirizine, montelukast sodium and other treatments; budesonide nasal spray nasal spray; nasal decongestant, such as 0.5-1% ephedrine drops to alleviate nasal congestion, the treatment is generally not more than 7 days; can be given to physiological salt water rinsing of the nasal cavity, to improve the blockage of the nose. 3. Deviated septum: Nasal congestion caused by deviated septum can be treated by surgery, such as septoplasty. 4. Nasal polyps: Nasal polyps lead to nasal congestion, you can consider nasal endoscopy to remove the polyp treatment, to promote the nasal passage. Nasal congestion affects sleep, it is recommended to consult a doctor in time to identify the cause of the targeted treatment.