Chronic leukemia, although it progresses more slowly than acute leukemia, is not easy to cure. Therefore, both acute leukemia and chronic leukemia are difficult to cure, except for chronic granulocytic leukemia and acute promyelocytic leukemia. 1. Chronic leukemia usually progresses more slowly than acute leukemia, and the symptoms may not be particularly obvious at the onset. Some patients may have non-specific symptoms such as fatigue and malaise. As the disease progresses, chronic leukemia tends to worsen gradually, and may progress to acute leukemia in the late stage. Chronic leukemia treatment drugs include imatinib (slow granules), ibrutinib (slow lymph), etc. Patients with slow granules are better treated with tyrosine kinase inhibitors and have a higher cure rate, while slow lymph is worse. 2. Acute leukemia is more difficult to cure due to faster disease progression and higher degree of malignancy, and the drugs include cytarabine and so on. However, acute promyelocytic leukemia is treated with all-trans retinoic acid, arsenic trioxide and other drugs, and the cure rate is higher. Specific disease treatment medication should be under the guidance of a physician.