5-year-old boy with enlarged mesenteric lymph nodes, should be targeted according to the severity of the symptoms; if the symptoms are not obvious, no special intervention; if the symptoms of bacterial infection is serious, it is necessary to be guided by the doctor for anti-infection treatment. 5-year-old boy mesenteric lymph node enlargement, if the symptoms are not very obvious, or there is no clear infectious factors; this situation does not require special treatment, you can target the local paste umbilical cord stickers, and pay attention to light diet, is conducive to alleviate the minor discomfort; in addition, it is recommended to pay more attention to the usual observation can be. If the bacterial infection symptoms are serious, such as fever, abdominal pain, nausea, vomiting and other symptoms, you should promptly go to the regular hospital, a clear diagnosis of the specific factors of infection, by the doctor’s guidance for anti-infective treatment, can be applied to cefixime, cefdinir and other antibiotics to control inflammatory reactions. For fever symptoms, application of ibuprofen, acetaminophen and other antipyretics. It is recommended that 5-year-old boys with enlarged mesenteric lymph nodes, when the symptoms are more obvious, seek medical treatment as soon as possible, after a clear diagnosis, to give targeted treatment and conditioning. The above medications should be used according to the doctor’s instructions.