The main causes of inability to have children are as follows: i. Male factors: such as the presence of sexual dysfunction, weak sperm, less sperm, poor sperm quality, etc. Female factors: 1. congenital absence of uterus: such as androgen insensitivity syndrome, that is, the appearance of female characteristics, but through chromosomal examination and other biological characteristics of male, basically infertile, is a relatively rare congenital anomalies; 2. other factors: such as ovulation disorders, fallopian tube incompetence, uterine adhesions and other inflammatory diseases caused by the obstruction of pregnancy channel. There are more reasons for inability to have children, which should be investigated one by one.