Patients with severe urinary tract infections can be treated with quinolones, cephalosporins, penicillins and other drugs orally or intravenously as prescribed by the doctor, but urine culture is also required and antibiotics can be selected according to the culture results. 1. Quinolones: patients can take oral levofloxacin tablets, moxifloxacin hydrochloride tablets, ciprofloxacin hydrochloride tablets and other quinolones as prescribed by the doctor to play an anti-inflammatory and antiseptic effect, and promote the recovery of urinary tract infection. 2. Cephalosporins: patients can take oral cefuroxime tablets, cefaclor tablets, cefdinir tablets and other cephalosporins as prescribed by the doctor, through the inhibition of bacterial cell wall synthesis to achieve antimicrobial effect, applicable to gram-negative bacilli caused by urinary tract infections. 3. Penicillin: patients can follow the doctor’s instructions to take amoxicillin capsules, ampicillin tablets and other drugs or intravenous input of injectable piperacillin sodium and other penicillin drugs treatment, play a role in killing bacteria, help urinary tract infection recovery. Serious urinary tract infection patients are recommended to go to the regular hospital in a timely manner, under the guidance of the doctor standardized treatment, do not self-medication.