Pain at the fistula after dialysis may be caused by local puncture abnormalities, blood-stealing syndrome, and internal fistula thrombosis. It can be treated by replacing the puncture point, general treatment, medication, surgery and other methods. 1. Local puncture abnormality: the forearm endocardial fistula of uremic patients, for puncture to maintain dialysis, if the puncture operation is improper, local compression is not complete, then there will be a sudden pain in the hand, blood seepage and so on. At this time, the puncture point needs to be replaced, and if the symptoms are not relieved after the replacement, consider re-establishing the fistula. 2. Stolen blood syndrome: vascular occlusion in the vertebral basilar artery, subclavian artery and other parts of the artery, arterial blood supply is insufficient, resulting in patients with cold hands, numbness and weakness, swelling, hand pain and other symptoms. For those with mild symptoms, pay attention to local heat preservation, appropriate wrist activities, and pay attention to observation. Ischemia is more serious, according to the condition of the choice of ligation of the radial artery or ligation of the distal end of the vein and so on. 3. Endovascular thrombosis: the pain at the fistula after dialysis may be organ ischemia, hypoxia, etc., and endovascular thrombosis occurs. You can apply urokinase or heparin sodium to dissolve the thrombus as prescribed by the doctor, or you can perform thrombectomy under local anesthesia. After dialysis fistula pain, it is recommended to go to the hospital in time, through the examination of the cause of the clear treatment, to avoid further aggravation of the condition.