Clinically, we call chronic renal failure a clinical syndrome consisting of a series of symptoms and metabolic disorders caused by the progressive irreversible decline of kidney function until the loss of function due to various kidney diseases. The end stage of chronic renal failure is often referred to as uremic syndrome. The causes of uremia are mainly the following categories: 1, various types of primary glomerulonephritis thylakoid proliferative glomerulonephritis, acute glomerulonephritis, membranous nephropathy, focal segmental glomerulosclerosis (FSGS), IgA nephropathy (with a genetic predisposition), etc. If not actively and effectively treated, eventually leading to uremia. 2, hypertension and diabetes 15% of hypertensive patients will be directly converted to uremic syndrome; 30% of diabetic patients will be complicated by diabetic nephropathy, eventually leading to diabetic uremic syndrome. 3, chronic kidney infectious diseases such as chronic pyelonephritis, renal tuberculosis, etc. 4, congenital kidney disorders such as polycystic kidney, hereditary nephropathy, and various congenital renal tubular dysfunction, etc. 5, chronic urinary tract obstruction, such as kidney stones, bilateral ureteral stones, urinary tract stenosis, prostate hypertrophy, tumors, etc. 6, secondary to systemic diseases such as renal arteriosclerosis, systemic lupus erythematosus complicated by lupus nephritis, allergic purpura nephritis, gout, etc. 7, other causes Renal vascular lesions such as renal artery stenosis, taking nephrotoxic drugs, and blind weight loss, etc. It is important to note that chronic glomerulonephritis accounts for 55.7% of all causes, becoming the primary cause of uremia.