Usually when chronic renal failure patients have gastrointestinal bleeding, the condition is more serious, usually need timely treatment. Gastrointestinal bleeding is a more common complication of chronic renal failure, and its incidence is significantly higher than normal, usually due to gastric mucosal erosion or peptic ulcer. At this time, the condition is more serious, some patients can appear hemorrhagic shock, multiple organ failure, and even life-threatening in severe cases, usually a poor prognosis. Patients with chronic renal failure are advised to seek medical advice in time if they have symptoms of gastrointestinal bleeding such as vomiting blood, blood in stool, black stool, etc. Under the guidance of specialists and after assessing the patient’s condition according to the patient’s symptoms, vital signs and relevant auxiliary examinations, the patient will be given symptomatic supportive treatments such as hemostasis, blood transfusion, and maintenance of stable internal environment in a timely manner so as to avoid delaying the condition.