Mycobacterial infections in women are difficult to cure at once and usually require 3-6 menstrual cycles of treatment to recover. Mycobacterial infection in women can lead to mycosis fungoides, which is characterized by increased and bean-like vaginal discharge, vulvar itching, vulvar redness and swelling, even accompanied by frequent and urgent urination. Patients need to stop using broad-spectrum antibiotics and estrogen in time. They can take antifungal drugs such as fluconazole orally, wash the vagina with 2% or 3% sodium bicarbonate solution and cleansing lotion, and use vaginal pessary such as dacrynic acid pessary and clotrimazole pessary for 7 days as a course of treatment, usually for 3-6 menstrual cycles. In addition, patients should avoid intercourse during treatment, avoid cold and spicy stimulating food, pay attention to personal hygiene, choose cotton underwear and change them daily, wash them with boiling water, keep the pubic area clean and dry, pay attention to rest, and sexual partners should be treated at the same time.