A high CCP is very likely to be rheumatoid arthritis because CCP is a specific antibody for rheumatoid arthritis. The presence of elevated CCP indicates a high likelihood of rheumatoid arthritis. If a patient has symmetrical joint swelling and pain in both hands and has elevated CCP, further screening for rheumatoid factor, blood sedimentation, C-reactive protein, etc. is needed. If elevated rheumatoid factor is present, along with indicators of inflammation, increased sedimentation and C-reactive protein, the diagnosis of rheumatoid arthritis will be clear. The most common and classic drugs are methotrexate and leflunomide, which can slow down the progression of joint disease.