Uric acid 438umol/L is on the high side. Currently, blood uric acid >420umol/L is defined as hyperuricemia, which is caused by excessive urate production or reduced uric acid excretion by the kidneys. Uric acid is a product of purine metabolism, so patients with hyperuricemia should first drink more water, preferably alkaline water, at least 2000-3000mL daily. In addition, it is necessary to have a low purine diet, do not drink beer, do not eat mutton, seafood, animal offal and other foods with high purine content, and carefully use drugs that inhibit uric acid excretion, such as thiazide diuretics. In patients undergoing radiotherapy and chemotherapy, the blood uric acid level must be closely monitored. If uric acid levels are not achieved with dietary control, choose drugs that excrete uric acid, such as benzbromarone, or drugs that inhibit uric acid production, such as allopurinol and febuxostat tablets.