The high mortality rate in the late stage of burns may be due to shock, renal failure, infection and other reasons. 1. Shock: After burns, due to increased vascular permeability, intravascular plasma will seep into the tissue space or under the epidermis, resulting in a decrease in effective circulating blood volume, and the patient will experience shock. Shock will lead to heart, liver, kidney and other organ dysfunction and failure, easily threatening the patient’s life. 2. Renal failure: due to the large amount of necrotic tissue in the burn wound, when the necrotic tissue is dissolved, it will lead to a large amount of toxin absorption, and the toxin is easy to accumulate in the kidneys, resulting in acute glomerular necrosis and other conditions, leading to renal failure, which affects the patient’s life. 3. Infection: patients with large-area burns are more prone to infection, which can easily lead to sepsis or even septicemia, thus leading to a high mortality rate in the late stage. The late recovery of burns is a slow process that takes a certain amount of time, and patients must be patient and cooperate well with the doctor’s treatment and the precautions instructed.