Sweating of the feet while sleeping may be caused by physiological reasons as well as by pathologic causes such as hyperthyroidism, tuberculosis, and drug factors. 1. Physiological reasons: too thick bedding and high ambient temperatures can lead to sweaty feet. 2. Pathological causes Hyperthyroidism: hyperthyroidism patients may have the symptoms of excessive sweating and fear of heat due to exuberant metabolism, in addition to irritability, fatigue, weight loss and other symptoms. Tuberculosis: tuberculosis patients with night sweats, low fever, fatigue as the main symptoms, tuberculosis patients will be accompanied by cough, chest pain and other symptoms, renal tuberculosis patients will be accompanied by urinary pain, urinary urgency and other urinary symptoms. Drug factors: tricyclic antidepressants, acyclovir, glibenclamide and other drugs can cause excessive sweating. If you sleep at night with abnormal foot sweating, it is recommended to go to the hospital in time to consult a doctor when physiological causes are excluded.