The common causes of numbness of the little toe of the right foot include localized compression, lumbar spine disease, vascular disease, etc., which can be relieved by medication and surgery. 1. Localized compression: If the shoes do not fit the feet, squeezing the little toes, standing or walking for a long time may cause numbness of the little toes, which can be relieved by resting or replacing the shoes with comfortable ones under normal circumstances. 2. Lumbar spine disease: Lumbar disc herniation and other diseases may cause numbness of little toes if they press on the nerve root. You should avoid weight bearing and excessive activities, choose a hard bed to rest, and take non-steroidal anti-inflammatory analgesics such as celecoxib and ibuprofen, etc. If the condition is serious, surgical treatment is needed. 3. Vascular diseases: Lower extremity vascular sclerosis, stenosis, embolism or occlusive vasculitis and other vascular diseases may cause numbness of the little toes, which need to be treated with different medications according to different conditions, such as the use of anticoagulant drugs such as warfarin. All of the above medications should be used under a doctor’s supervision. Numbness of the right little toe may also be caused by other reasons, once the numbness is intense or cannot be relieved, you should go to the hospital in time to find out the cause and carry out targeted treatment.