Wisdom tooth inflammation requires local rinsing and medication along with systemic anti-inflammatory treatment. During the eruption of wisdom teeth, the teeth cannot fully erupt due to lack of space, and part of the teeth are covered by gums, forming blind pockets. If the brushing is not thorough or the oral hygiene is not good, the bacteria in the blind pockets breed and pericoronitis of wisdom teeth appears, and pericoronitis of wisdom teeth requires timely anti-inflammatory treatment. If the pericoronitis is limited to the area around the crown and there is no systemic inflammation spreading, a local rinse around the crown can be applied, using hydrogen peroxide to thoroughly rinse the bacteria in the blind pocket as well as the food residue, and then the gums are locally coated with iodine glycerin. If pericoronitis recurs or irreversible damage is done to the anterior teeth, extraction of the wisdom tooth can be considered after the inflammation is controlled. If the wisdom tooth obstruction is not severe, the wisdom tooth can be retained if it can erupt by removing part of the gum. If the wisdom tooth pericoronitis spreads further and invades the masticatory muscles with restricted mouth opening, or if there are systemic symptoms, such as fever or sepsis, systemic anti-inflammatory treatment is required. Penicillin can be used for sedation. Therefore, inflammation of the wisdom teeth can be treated with local irrigation, application of iodoglycerin, or penicillin drip.