Vomiting and diarrhea are symptoms of acute gastroenteritis, mostly caused by cold and flu leading to gastrointestinal dysfunction, or eating fried, spicy and stimulating food leading to nausea and diarrhea. The following points need to be noted: 1, pay attention to drinking more water, pay attention to local hot compresses, drinking water can replenish water electrolytes, prevent water electrolyte disorders, local hot compresses can reduce intestinal spasm, reduce the symptoms of diarrhea. 2, give drug treatment, clinically commonly used are montelukast, loperamide hydrochloride capsules, anti-diarrheal symptomatic treatment, bifidobacterium typhimurium capsules to regulate intestinal flora. If accompanied by fever, norfloxacin capsules need to be given. Meanwhile, for severe vomiting, metoclopramide hydrochloride injection 10mg can be given intramuscularly to improve the symptoms. If there is no relief repeatedly, it is better to improve the blood routine and electrolyte analysis and other tests. If there is an increase in blood count or electrolyte disorder, intravenous fluids, rehydration, anti-inflammatory and symptomatic treatment are needed.