Spot removal creams may have some effect, but there is a lack of sufficient scientific evidence. It is recommended to take physical therapy and other means under the guidance of a doctor and pay attention to sun protection in general. Cosmetics cannot claim medical effects and have no therapeutic effects, so please use them with caution. It is recommended to use them only if you are sure that the ingredients are safe. Meanwhile, cosmetics are only applied on the surface of the face and are less absorbed externally through the skin, making it difficult to play an ideal role in removing pigmentation. Pigmentation is a pigment disorder skin disease caused by many factors, the effect of external drug treatment is limited, usually under the guidance of doctors, combined with their own conditions, taking into account the age, heredity, the type of pigmentation, etiology, etc., a combination of various means of treatment, in order to achieve a more ideal effect of pigmentation. At present, for freckles, age spots, chloasma, etc., laser spot removal through medical cosmetology is a more effective method, but it must be correctly selected under the guidance of professional doctors. In daily life, patients with pigmentation usually pay attention to good sun protection, develop regular work and rest, avoid staying up late and keep a good mood. Therefore, the use of skin care products and topical medications to remove pigmentation generally has limited effect in lightening pigmentation. Patients who have the need to get rid of pigmentation are advised to go to the hospital for consultation and choose the appropriate treatment plan under the guidance of professional doctors, and avoid self-medication and blindly believing in biased prescriptions, so as not to bring unnecessary risks.