There is no such thing as “Shuanghuanglian or Qingkailing”. The composition, efficacy and treatment of the two drugs are different, and there is no difference between good and bad. The drug should be used under the guidance of a doctor. The two Huanglian granules are composed of honeysuckle, forsythia and astragalus. The combination of the above medicines has the efficacy of dispersing wind and relieving surface, clearing heat and removing toxins. It is often used in the treatment of colds and flu caused by external wind-heat, with symptoms of fever, cough and sore throat. Pregnant women and people with cold spleen and stomach should not use it. Qingkailing is Qingkailing Granules, which is composed of mother-of-pearl, Panlangen, buffalo horn and other medicines. The combination of the above medicines has the effect of clearing away heat and removing toxins, calming and tranquilizing the mind. It is often used in the treatment of high fever, restlessness, sore throat and so on. Caution should be exercised when diarrhea occurs in patients with prolonged illness and body weakness. Different medicines are generally not comparable, and it is recommended that proprietary Chinese medicines be taken under the guidance of a professional Chinese medicine practitioner.