Men with itching and pain in the urethra are most likely to have a non-gonorrhea infection. It is recommended to do a discharge test. It is recommended not to urinate in the morning and then go to the hospital to take urethral discharge and look for mycoplasma, chlamydia and gonococcal test can effectively confirm the diagnosis, if mycoplasma and chlamydia are positive, this is the possibility of non-gonorrhea infection. It is recommended that you can use azithromycin, roxithromycin, minocycline, doxycycline and other oral medications, which can effectively treat non-gonorrhea infection for 7-10 days. During the treatment period, you should not drink alcohol and eat spicy and irritating food, and it is recommended that your spouse should be treated at the same time.