Monkeypox rash usually grows on the face, palms, feet, oral mucosa, genitals, conjunctiva and cornea. The most common areas of monkeypox rash are on the face, where about 95% of the patients will develop the rash. Secondly, the rash is also found on the palms of the hands as well as the soles of the feet in about 75% of cases. In addition, the rash is also found on the oral mucosa, which interferes with the patient’s ability to eat. In addition, the genitals, conjunctiva and cornea of the eye are also involved to varying degrees. The monkeypox rash initially appears as a papule with a flattened base, and the rash may sequentially pass through macules, papules, herpes, pustules, and finally crusts, which may leave a scar. These herpes are present for about 10 days and can then crust over and fall off. Some patients can have bacterial infections due to poor herpes care, leading to symptoms such as pus. Patients with symptoms related to monkeypox virus infection should seek medical attention and treatment as prescribed by their doctor.