Thiazide type/thiazide-like diuretics, long-acting CCB or ARB monotherapy should be preferred in patients with monosystolic hypertension. Patients with coronary artery disease should avoid diastolic blood pressure below 60 mmHg while pursuing systolic blood pressure compliance to avoid aggravating myocardial ischemia. The target value for lowering blood pressure in patients with non-diabetic nephropathy is <140/90 mmHg; ACEI or ARB is preferred in patients with proteinuric nephropathy; thiazide diuretics can be combined if necessary, and Xiang diuretics can be combined in patients with excessive volume load. The target value of blood pressure lowering for diabetic patients is <130/80 mmHg; ACEI or ARB is preferred for those with cardiovascular disease or renal disease or other cardiovascular risk factors; ACEI, ARB, dihydropyridine CCB or thiazide diuretics are preferred for other diabetic patients.