Every part of the human body has its own irreplaceable role, such as the skull. The skull builds a defensive wall for the brain tissue to prevent it from being attacked by the outside world. However, accidents, such as traffic accidents, falling objects, etc., can easily lead to traumatic brain injury, traumatic brain injury surgery, sometimes due to increased intracranial pressure and the need to remove the bone flap decompression. When a piece of skull is missing, the integrity of the cranial cavity is damaged, and the intracranial environment and intracranial pressure become very unstable. Is it necessary to repair the skull after it has been removed? A defective skull will affect the circulation of cerebrospinal fluid and blood in the skull, and the nerve function of the brain will be impaired, which will induce a series of craniosynostosis syndromes. The patient may experience dizziness and headache, numbness and weakness in the limbs, and irritability. In addition, cranial defects will also have a certain impact on the patient’s vision, hearing and sense of smell, and in severe cases, may also induce seizures. Therefore, in order to minimize the damage, it is recommended to go to the hospital as soon as possible to have a skull repair surgery, which aims to rebuild a closed and intact cranial cavity to ensure that all brain functions can be performed normally. However, to do skull repair surgery is very important is the choice of materials, at present to do skull repair surgery is more ideal is polyether ether ether ketone PEEK material, this is an advanced polymer material, all the performance is very excellent, the shape effect is also very good. We are currently in the cranial bone repair surgery on the more use of PEEK material, and our team continues to explore, and technical improvement and upgrading and material optimization design, the introduction of cosmetic surgery concept, comprehensive PEEK cranial bone repair plastic surgery, achieved very good clinical results.