Complex coronary artery disease refers to a variety of more difficult types of coronary artery disease, such as complex lesions, more serious degree, the effect of Western drug treatment is not good, coronary artery multi-branch lesions or lesions diffuse, can not be stented or contraindications to coronary artery bypass grafting and other more difficult types of coronary artery disease. Due to the complexity of this type of patient’s condition and the poor therapeutic effect, patients are very confused. Chinese medicine for this disease, the use of evidence-based treatment, combined with modern pharmacological research, given a large dose of tonifying qi, phlegm, blood circulation and blood stasis class of drugs, often can receive satisfactory clinical efficacy. So, how to use the medicine for this kind of patients? My experience is to use large doses of drugs. According to the modern people’s diet of greasy, fat, sweet and thick taste, the body of phlegm and dampness, I often prescribe gua gua gua allium bracteatum and half-sia soup and danshen drink, or and tonifying the yang to restore the five Tang plus subtractions in order to take to open phlegm and open the knot, activate the blood and open up the efficacy of the veins. I often prescribe 20-30 grams of Allium guajava, 15-30 grams of Semixia (which is toxic and commonly used in quantities of less than 15 grams), 30 grams of Danshen, 30-60 grams of Pueraria lobata, 3-6 grams of leech powder and Panax quinquefolium, 20-30 grams of Dilong, and in cases of obvious qi deficiency, 30-120 grams of Astragali, and then according to the patient’s condition, 20-30 grams of Rhizoma Polygonatum, 15-30 grams of Radix et Rhizoma Pinelliae and according to the condition of lipid, 15-30 grams of Gastrodiae Vulgare. According to the condition of blood lipid, add 15-30g of gynostemma, 15-30g of fried hawthorn, 10-20g of lotus leaf, 20-30g of He Shouwu, and then add 15g of chicken inside gold, 15-20g of fried malt, 15-30g of corrugated seeds to strengthen the spleen, eliminate food and protect the stomach, and so on, after hundreds of cases of observation, the effect is satisfied. Case: Wang Moumou, male, 66 years old, Tangyin County, Henan Province, the patient in 2013 due to coronary artery disease in Anyang Regional Hospital, Department of Cardiology coronary angiography suggests that the coronary artery in many serious lesions, and the right coronary artery, the anterior descending branch of the implantation of a number of stents, implantation of clopidogrel tablets given to clopidogrel tablets, aspirin tablets, Atorvastatin Calcium tablets and other drugs to control the condition of the stability of the disease, but the patient’s symptoms did not see a reduction in the symptoms of the patient, and then went to the hospital of traditional Chinese medicine, after taking 20 payments of Chinese medicine to completely eliminate symptoms. The symptoms completely disappeared after 20 doses of traditional Chinese medicine. The patient stopped using clopidogrel tablets after one year of stenting, and continued to take atorvastatin and other medications, at the end of August 2015, suddenly appeared chest tightness and chest pain, sweating discomfort, and aggravated by movement, and urgently went to the Department of Cardiology of Anyang Regional Hospital to seek treatment, and diagnosed acute myocardial infarction, and the review of coronary angiography suggested that the distal right coronary artery is occluded, and the anterior descending branch is occluded in the stent, and the opening of the intermediate branch is 80% stenosis, and the patient was given low molecular heparin, Low molecular heparin, aspirin enteric-coated tablets, clopidogrel tablets and other medications were given to the patient, and it was found that the patient had multiple petechiae with a diameter of 2-5 cm, with warm skin and itching in the middle, and the platelet count was normal, and the patient was considered to be allergic to antiplatelet drugs, and the symptoms disappeared very quickly after discontinuing the use of aspirin and boleolevir and were aggravated by reoccurrences, and the patient could not undergo coronary stenting and bypass grafting treatment (anticoagulant and antiplatelet therapy were needed after the operation). It was very difficult to treat the patient, and western medicine was unable to help. At the strong request of the family, the patient was transferred to the Department of Cardiology of our hospital for treatment. At first, the patient was considered to have serious lesions, and after retesting with clopidogrel tablets, the patient’s rash immediately recurred, and after consultation with experts in the department, it was decided that no more antiplatelet drugs should be applied, and combined with the patient’s tongue, pulse, and symptoms, the patient was recognized as having qi deficiency, phlegm and blood stasis, and was treated with the following treatment principles: benefiting qi and activating blood, and eliminating phlegm and opening up the stagnation. Chinese medicine treatment was given, prescription: Astragalus 50g, Allium cepa 30g, Allium cepa 20g, Fagopyrum 15g, Fried Citrus aurantium 15g, Pueraria Mirifica 30g, Salviae Miltiorrhizae 30g, Safflower 15g, Panax ginseng Powder 3g(flush), leech Powder 3g (flush), Gynostemma 30g, Sambucus nigra 30g, Cinnamon twig 3g, Rhizoma Coptidis Tablet 6g, Succus nigra 6g(flush), 5 doses, decocted with water, one dose per day, divided into Three doses, the patient took a dose of heart and chest feel free, 5 doses, chest tightness basically disappeared, can be in the ward activities, consider effective, the original formula plus astragalus to 50g, continue to take 5 doses, the condition has improved significantly, you can walk freely in the ward, occasional fatigue, petechiae on the body, adjust the prescription for: astragalus 90g, the whole Psidium guajava 30g, Allium bakeri 30g, Faganxia 15g, fried Hovenia caryophyllus 15g, Pueraria Mirifica 40g, Pueraria Mirifica 40g, Pseudostemma Gastrodiae, Pseudostemma Gastrodiae. 15g, Pueraria lobata 40g, Salvia miltiorrhiza 30g, saffron 15g, Panax ginseng powder 3g (punch), leech powder 4g (punch), gibberellic acid 30g, Morus alba 30g, cinnamon stick 20g, Huanglian tablet 6g, amber 6g (punch), baked licorice 6g, Qiangwu 10g, chickweed vines 30g, American ginseng 10g, Rhodiola rosea 30g 5 doses, decoction, 7 doses, the patient recovered on September 23rd! The patient was discharged from the hospital and could walk more than 500 meters at a fast pace without symptoms. After the patient continued to take Chinese medicine modulation, the current physical condition is good.