Blisters generally refers to blisters, feet long blisters may be tinea pedis, sweat herpes and palmoplantar pustulosis and other diseases caused by the patient is recommended to take general treatment, medication and other ways to improve. 1. Tinea pedis: blisters on the feet may be caused by tinea pedis, patients should pay more attention to hygiene, do not share daily necessities with others, to avoid contagion. Follow the doctor’s instructions can choose imidazole antifungal drugs, such as miconazole, ketoconazole and so on to smear the affected area, has the role of antifungal. 2. Sweat herpes: foot blisters may be caused by sweat herpes, the patient should avoid contact aggravation, reduce the adverse stimuli. Follow the doctor’s advice to use appropriate calcium-modulated phosphatase inhibitors, such as tacrolimus ointment, bared mecamylamine cream, etc., which has the effect of stopping itching and eliminating inflammation. 3. Palmoplantar pustulosis: blisters on the feet may be caused by palmoplantar pustulosis, patients should pay attention to the cleanliness and hygiene of the broken skin to avoid skin irritation. Follow the doctor’s instructions to use topical glucocorticoid drugs to smear the affected area, such as hydrocortisone, dexamethasone, etc., with anti-inflammatory, antipruritic effect. There are many reasons for the blisters on the feet, it is recommended that patients seek medical examination, clear causes, with the doctor standardized treatment.