When doing biopsy the test result is large and deep stained nuclei, which is a way of describing cytological examination, is abnormal and is due to the following reasons: First, it may be inflammatory cells, once diagnosed it is necessary to carry out timely anti-inflammatory and anti-inflammatory treatment. Secondly, the cells are considered to have a malignant tendency and need to be examined to rule out the chances of having a malignant tumor. This condition can result in large enlargement and deep staining of the nucleus of the cells in particular areas. Thirdly, it may be a normal cell aging and apoptosis process, which is a normal phenomenon. Fourthly, if women need to pay attention to the possibility of cervical cancer, they can go to the hospital for further tissue biopsy to confirm the disease and then take corresponding methods for treatment once it occurs.