Gastroscopy shows that bile reflux refers to the patient’s bile, pancreatic fluid and digestive juices, from the pylorus reflux into the stomach triggered by the gastric mucosal damage, and ultimately lead to chronic gastritis, and bile reflux gastritis is often synchronized with the onset of chronic superficial gastritis. The symptoms of bile reflux gastritis are mainly manifested as heartburn, acid reflux, nausea, burning sensation in the upper gastrointestinal tract, vomiting, flatulence, etc. After gastroscopy to confirm that the bile reflux must be timely intervention to avoid long-term bile reflux resulting in chronic gastritis. For patients with bile reflux can take oral mosapride, domperidone, omeprazole, ranitidine and other drugs for treatment, and at the same time pay attention to diet, and be ready for regular review.