The reasons for not waking up after general anesthesia surgery generally include: overdose of anesthetics, patients with cerebral hypoxia, carbon dioxide retention, cardiovascular and cerebrovascular accidents, patients with hypoglycemia and other conditions. 1. Overdose of anesthesia drugs: the anesthesia drug dosage is too large or too strong, the patient’s age, body weight, preoperative mental state is poor, liver and kidney insufficiency, etc. can make the wakefulness of the delay. 2. Cerebral hypoxia: if the patient is not well managed during anesthesia, the patient may suffer from mild cerebral hypoxia, and the awakening will be delayed after the operation. 3. Carbon dioxide retention: patients with poor ventilation and hypoxia will have carbon dioxide retention, which will lead to non-wakefulness after general anesthesia surgery. 4. Cardiovascular and cerebrovascular accidents: If the patient has a cardiovascular and cerebrovascular accident during the operation, the most common one is cerebral thrombosis, and the awakening after the operation will be delayed. 5. patients with hypoglycemia: more patients with diabetes, if the patient’s blood sugar during surgery is relatively low, there is no timely correction, post-operative awakening will also be delayed. General anesthesia surgery anesthesia should be preoperative assessment of the patient’s physical condition, choose a good anesthesia program; anesthesia carefully operated, do a good job of vital signs monitoring; postoperative anesthesia as soon as possible to stop the injection of anesthetics.