The first step in determining whether itraconazole is effective in treating gray nails is to determine what type of disease it is. Gray nails are caused by fungal infections that attack the nails, and these fungal infections include Trichophyton rubrum as well as Trichophyton epidermidis. When gray nails occur, the fungus must first be addressed, and current treatments for the fungus include topical medications, antifungal preparations, and oral antifungal medications. Topical antifungal medications include ketoconazole or econazole these creams and apply them yourself, as well as oral itraconazole, an antifungal stimulus stimulation for treatment, and itraconazole has a stronger penetrating effect and is more effective for gray nails. In addition, it must also be noted that for gray fingernails for antifungal treatment, the course of treatment must adhere to more than four weeks, otherwise it is easy for gray fingernails to recur, and at the same time for antifungal treatment, but also to control their diet, to adhere to a light diet. In addition, for gray nails, do not carry out excessive scratching, massage these actions, may cause the spread of gray nail fungal infection.