Pseudopyloric hyperplasia is mostly due to chronic atrophic gastritis, and the etiology and pathogenesis of chronic atrophic gastritis are generally considered to be under the influence of immune factors, bile reflux, biological factors, drug factors, and acute gastritis, oral and nasopharyngeal infections, combined with emotional and mental disorders, poor diet, excessive fatigue, insomnia, and cold, which cause chronic inflammation of the gastric mucosa, causing the gastric mucosal surface to be repeatedly Damage to the gastric secretion gland atrophy, gastric mucosa discoloration, thinning, vascular exposure, reduced gastric acid secretion, weakened digestive function, gastric peristaltic dysfunction, etc., thus forming chronic atrophic gastritis. In Chinese medicine, the basic pathological mechanism of chronic atrophic gastritis is the weakness of the spleen and stomach and the congestion of qi. Yin deficiency in old age, internal injuries, dietary phlegm accumulation, and prolonged illness causing stasis can all impair the function of the spleen and stomach, resulting in weakness in lifting and lowering, and poor qi flow, resulting in symptoms such as distension, vague pain, poor appetite, and weakness in the stomach and epigastric region. This disease is a deficiency of the root and the symptoms are mixed with cold and heat, with the deficiency of the root, the more deficient the evil is, the more deficient the evil is, the more deficient the evil is, often affecting each other and difficult to heal quickly. May be related to the following factors: 1, the continuation of chronic superficial gastritis: chronic atrophic gastritis can be developed from chronic superficial gastritis. The PLA General Hospital and six other hospitals reported 164 cases of superficial gastritis after 5 to 8 years of follow-up observation, of which 34 cases turned into chronic atrophic gastritis (20 .7%). The etiology of chronic superficial gastritis can be a causative and aggravating factor of chronic atrophic gastritis. 2, genetic factors: according to Varis survey, the incidence of chronic atrophic gastritis is significantly higher among the first generation of relatives of patients with chronic atrophic gastritis, and the genetic factor of pernicious anemia is also evident. The incidence rate with relatives is 20 times greater than the control group, indicating that chronic atrophic gastritis may be related to genetic factors. Polmer called it excretory gastritis. In addition to lead, many heavy metals such as mercury, tellurium, copper and zinc have certain damaging effects on the gastric mucosa. 4, radiation: radiation therapy ulcer disease or other tumors, can make the gastric mucosa damage or even atrophy. 5, iron deficiency anemia: many facts show that iron deficiency anemia and atrophic gastritis are closely related, Badanoch reported 50 cases of iron deficiency anemia, normal gastric mucosa, superficial gastritis and atrophic gastritis accounted for 14%, 46% and 40% respectively. However, the mechanism of gastritis caused by anemia is not known. Some scholars believe that gastritis is the primary cause, because gastritis has low gastric acid, resulting in the inability to absorb iron, or the formation of anemia due to gastric bleeding; another opinion believes that anemia is present first, because the lack of iron in the body affects the renewal rate of gastric mucosa and predisposes to inflammation.