The causes of nose bleeding that won’t stop are mostly considered to be nasal factors or systemic factors. Nasal factors include ruptured blood vessels in the nasal cavity, deviated septum, rhinitis, and nasal tumors. Systemic factors can be abnormal coagulation mechanism, also can be seen in the case of elevated vascular pressure. 1. Nasal diseases: nose bleeding can not be stopped, this situation is first seen in the rupture of nasal blood vessels, the rupture of the capillary network in the anterior or posterior part of the nasal cavity, resulting in continuous bleeding. Inflammation of the nasal cavity or deviation of the nasal septum can also lead to bleeding in the nose. Tumors of the nasal cavity, especially hemangioma of the nasal cavity, can also lead to nose bleeding. 2. Abnormal coagulation mechanism: Systemic factors include leukemia, thrombocytopenia, hemophilia, in these cases, the patient’s body coagulation system is abnormal, coagulation dysfunction, nose bleeding will be difficult to stop. 3. Hypertension: If the patient has a history of hypertension, the systemic arterial blood pressure rises, the intravascular pressure is high, causing the nose capillaries to rupture, and the symptom of unstoppable bleeding will also occur. If you find that the nose bleeding can not be stopped, you should promptly go to the hospital, first to stop bleeding, and then check the cause of bleeding, and targeted treatment.