Toe seam ulcers and itchy, if it is tinea pedis, you can use boric acid solution, miconazole and other treatments; if it is eczema, you can use furacilin, zinc oxide oil and other treatments. 1. Tinea pedis: fungal infection caused by toe ulcers and itchy, can be used first boric acid solution and other wet compresses, followed by topical miconazole or biphenylbenzazole powder, after the lesions are dry and then topical cream. 2. Eczema: eczema caused by toe ulcers and itchy, if the erosion and oozing more can use saline or boric acid solution and other detergents wet compresses; there are vesicles but not much oozing can be used when the zinc oxide oil, glucocorticoid cream. Toe crack ulceration and itching may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or standardized treatment.