Jaundice classification: jaundice is divided into physiological jaundice, pathological jaundice, breast milk jaundice. Characteristics of pathological jaundice in newborns: (1) Early appearance: it begins to appear within 24 hours after birth. (2) Jaundice value rises too fast: jaundice develops too fast, rising more than 5 mg/dl per day. (3) Jaundice lasts longer: full-term infants do not subside in twenty days, premature infants do not subside at full term. It is even accompanied by anemia, abnormal body temperature, poor milk intake, vomiting, abnormal color of urine and stool. (4) Jaundice receding and reappearing: some jaundice has subsided or reduced and then reappeared and worsened, mostly pathological jaundice. (5) Laboratory tests: high combined bilirubin, more than two milligrams per deciliter. (6) History of adverse maternity: i.e., other children presenting with death due to excessive jaundice. (7) Prenatal high-risk factors: e.g., the child has hemolysis. Causes of pathological jaundice: Excessive bilirubin production in newborns, low liver uptake and/or conjugated bilirubin, and impaired excretion of bilirubin can all cause pathological jaundice in newborns. The main diseases causing pathological jaundice include hemolysis, congenital biliary atresia, insufficient glucuronosyltransferase activity, sericosis, neonatal hepatitis, and neonatal sepsis. Treatment and healing: The current treatment for pathological jaundice includes etiologic therapy, pharmacotherapy, phototherapy, and blood exchange therapy, which need to be targeted according to the specific onset of the disease. The vast majority of pathological jaundice can be completely cured, but it also depends on the timeliness and effectiveness of treatment. If jaundice is not treated in a timely manner, complications can easily arise and can lead to “nuclear jaundice”, which can not only damage the baby’s nervous system, but can also endanger the baby’s life in severe cases.