Rough and black elbow skin may be caused by physiological factors or pathological factors (such as acanthosis nigricans, etc.), which need to be treated according to the specific causes, and general treatment and medication should be taken after clear diagnosis. 1. Physiological factors: rough and black elbow skin, need to consider the elbow due to long time friction, stimulation, resulting in local melanin deposition, or due to the elbow has more folds, daily cleaning is not in place. Patients need to reduce the elbow friction, at the same time do a good job of local hygiene, daily sunscreen, without special treatment. 2. Pathological factors: elbow skin rough black may be due to acanthosis nigricans, the cause of the disease is unknown, may be genetic, obesity, diabetes, drugs and other related. It is recommended that patients control diet, reduce weight, can be long-term oral vitamin A, local use of vitamin A cream for coating and other treatment methods, so as to improve the phenomenon of melanin deposition. The causes of rough and dark elbow skin are different, and so are the treatments. If the patient excludes physiological factors, it is recommended that the patient go to the hospital for a clear diagnosis, and use medication under the guidance of the doctor, do not use it indiscriminately, so as not to lead to adverse consequences.