If the large platelet ratio is high and there are no other symptoms, it is usually fine and no treatment is needed. If the large platelet ratio is high and there are abnormalities in platelets and coagulation function, relevant examinations should be completed, and targeted treatment should be carried out after the diagnosis is clear. Large platelet ratio refers to the proportion of large platelets to total platelets. Physiological changes: large platelet ratio can be transiently elevated after exercise and meal, and can be recovered after rest. 2. Pathological changes: high large platelet ratio and abnormal platelet and coagulation function may be related to acute septic infection, acute blood loss with high large platelet ratio, hemolytic anemia after splenectomy, and true erythrocytosis. Relevant examinations should be improved, and targeted treatment should be carried out after the diagnosis is clear. In daily life, we should maintain good living habits, try to eat a light diet, reduce the intake of high-fat, high-sugar foods, and consume more fresh vegetables and fruits.