The causes of sudden generalized weakness may be hypotension, hypoglycemia, electrolyte disorders, hypokalemia, hyponatremia, and cerebrovascular diseases. 1. Hypoglycemia will lead to insufficient supply of energy to the body in a short period of time, at this time, generalized weakness and tenderness will occur, and symptoms such as panic and hand tremor may also occur. 2. Postural hypotension may cause transient ischemia of the brain leading to dizziness and weakness. 3. Electrolyte disorders that occur in the body for various reasons (e.g. diarrhea, fever) may also cause weakness. 4. When the blood potassium is low to a certain extent, hypokalemia will occur, and weakness will occur; when hyponatremia occurs, osmotic pressure will be changed, and generalized weakness and tenderness will also occur. 5. For example, transient ischemic attack leads to insufficient cerebral blood supply, which can be manifested as generalized weakness and tenderness. Therefore, when patients have these problems, they must consult the doctor early for relevant examinations to clarify the cause of the disease and then carry out symptomatic treatment.