Autologous fat transplantation has been particularly hot lately, and the beautiful women with perfect faces seen on the road generally have almost one surgery in hand, and more than two or three fillings. In fact, not only the candidates who underwent the surgery, that is, there are many plastic surgeons have also expressed doubts about the effectiveness of fat filling treatment. A, fat transplantation is a safe and effective surgery The full name of fat filling is “autologous granular fat transplantation”, a form of tissue transplantation, because the fat tissue is easy to disperse into liquid droplets with mobility, so it is often called injection filler, is a relatively simple method of tissue transplantation. The process of separating and purifying fat cells can be divided into static method, centrifugation method, filtration method, etc.; in addition, some methods are currently called adipocyte-assisted techniques, including the addition of growth factors, PRP platelet-rich plasma, and ADSC adipose-derived mesenchymal stem cells to the injected fat cells. This results in a better textured, smoother and more delicate skin after injection. In fact, fat cell transplantation is used in a wide range of applications, including breast reconstruction, scleroderma, and scarring with good results. Cosmetic applications receive more attention because of the greater publicity, but it is not true that fat transplantation is used only in cosmetic surgery. As far as fat injection filling is concerned, it can be considered as a safe and effective cosmetic surgery. Secondly, thinness requires more skill from doctors So what kind of people are suitable for autologous particulate fat filling treatment? By and large, people with more body fat are more suitable for this procedure, which means that the person is unevenly distributed fat, rather than lacking fat. The fat source is more sufficient and the survival or volume occupancy of fat cells will be better. Contradictory to the actual situation: many people who need fat transplantation are very thin, and the fat source from their own body is not very sufficient, which puts higher requirements on the doctor, such as extracting fat more effectively, reducing fat cell depletion, and improving the efficiency of fat filling. Third, do not lose weight before surgery Another point is that it is also important to avoid drastic weight loss before and after lipofilling and to ensure adequate nutritional intake. At present, there is a buzzword in academic circles, fat metabolism disorder (lipodystrophy), which refers to the problem of fat metabolism and transfer, the hoarding of heterologous adipose tissue in liver and muscle tissue, the emergence of insulin resistance (diabetes) and a series of other situations, and research has found that calorie (calorie) intake and autologous fat content are a pair of problems, if too much or too little autologous fat will affect the fat transfer, which means that proper retention of autologous fat (not to be too thin) is protective for the body. From this perspective, maintaining a healthy and beautiful image is not the thinner the better, the key is the ratio and distribution of fat, fat transfer is an immediate way to adjust the distribution of fat. Fourth, fat filling can be anti-aging Autologous particles, in addition to improving the proportional structure, also have a very obvious improvement on the appearance of aging in older people. A recent study on facial aging concluded that facial aging is caused by several factors, including atrophy of deep fat pad, laxity of ligament system, atrophy of superficial subcutaneous fat and intercellular matrix, and change of skin surface. Lipofilling can improve several of these factors, including atrophy of the deep tissue, atrophy of the subcutaneous tissues, and the coloration of the superficial skin layer. It has been noted that the inflammatory response developed during fat injection filling and the stem cells (mature precursor cells with the ability to differentiate) in the adipose tissue can improve the strength of the ligament system, so the laxity process is found to be delayed and postponed in the long term observation. This means that after fat injection fillers can significantly improve the appearance, even if it does not improve the sagging and laxity in the short term, but it can improve the sagging and laxity caused by aging in the long term. The premise of all this is not to overfill, and reasonable and staged filling for anti-aging is safe and effective. In conclusion, autologous particulate fat filling or transplantation, after years of clinical practice and research, has seen many improvements in surgical methods, significant improvements in results, and a gradual expansion in the scope of application, which has many applications in anti-aging, regulation of metabolism, and restoration of tissue repair functions, in addition to cosmetology. The technology of fat extraction and separation has become increasingly mature, which is an ideal method to improve the proportion of facial tissue structure conveniently, quickly and effectively.