The indicators of thyroid function tests include the following.
TT3 serum total triiodothyronine, a sensitive indicator for early GD, observation of efficacy during treatment and relapse after discontinuation of medication, and a specific indicator for the diagnosis of T3 hyperthyroidism. Normal values in adults: RIA method 1.8-2.9nmol/l (115-90ng/dl) ICMA method 0.7-2.1nmol (44.5-136ng/dl) Siping First People’s Hospital, Department of Nuclear Medicine, Zheng Song stop TT4 The most basic in determining thyroid function is the screening index. 65-156nmol/l (5-12ug/dl) by RIA method ICMA method 58.1~154.8nmol/l (4.5~11.9). FT3 Sensitivity and specificity are significantly higher than total T3 (TT3). Normal values in adults: RIA method 3-9 nmol/l (0.19-0.58ng/dl) ICMA method 2.1-5.4 nmol (0.14-0.35ng/dl) FT4 Sensitivity and specificity were significantly higher than total T4 (TT4). Normal values for adults: RIA method 9-25nmol/l (0.7-1.9ng/dl) ICMA method 9.0-23.9nmol (0.7-1.8ng/dl) TSH reflects changes in thyroid function more rapidly and significantly than T3 and T4. Normal values for adults: IRMA method (high sensitivity) 0.4 to 3.0 or 0.6 to 4.0mu/l ICMA and TRIFMA are more sensitive than IRMA, called ultrasensitive TSH, normal range: 0.5 to 5.0mu/l TGAb if persistently positive for a long time with high titer, suggesting that the patient has the possibility of progressing to autoimmune hypothyroidism. TMAb thyroid microsomal antibodies, now generally known as “thyroid peroxidase antibodies – TPOA”. Functional diagnosis: Increased blood FT3 and FT4 (TT3 and TT4) and decreased TSH (<0.5 mU/L) are consistent with hyperthyroidism; only increased FT3 or TT3 with normal FT4 and TT4 can be considered as T3 hyperthyroidism; only increased FT4 or TT4 with normal FT3 and TT3 is T4 hyperthyroidism; decreased blood TSH with normal FT3 and FT4 is consistent with subclinical hyperthyroidism. Hyperthyroidism. Ultrasound examination of the thyroid gland (1) can be used as a measurement of the size and volume of the thyroid gland. (2) Identify whether the thyroid nodule is substantial or cystic, and determine the location, size and depth of the mass. If the ultrasound shows that the mass contains fluid and the cyst wall is thin and smooth, the possibility of malignancy is low and can be treated by ultrasound-guided aspiration of the cystic fluid by puncture. (3) Isolated nodules or multiple nodules can be detected, and the size of the nodules can be measured. (4) To assist in identifying benign and malignant tumors of the thyroid gland. In patients with postoperative thyroid cancer, recurrent or metastatic lesions that cannot be palpated can be detected. CT examination of the thyroid gland (1) Assists in the diagnosis of thyroid adenoma. (2) It helps to diagnose thyroid cancer and also detects enlarged deep cervical lymph nodes due to thyroid cancer metastasis. Advanced thyroid cancer can metastasize to the cranium, lung and skeletal system, which can be easily detected by CT examination, thus providing valuable information for clinical treatment and prognosis assessment. (3) Multiple endocrine neoplasm (MEN) type IIA, also known as Sipple syndrome, includes medullary thyroid carcinoma, pheochromocytoma and parathyroid adenoma or hyperplasia. Type IIB includes, in addition to medullary thyroid carcinoma and pheochromocytoma, multiple mucosal fibromas. For MEN IIA and IIB, CT examination can not only further confirm the clinical diagnosis, but also show the location, number and size of multiple endocrine tumors, which can provide valuable information for clinical treatment. (4) CT examination helps to detect multiple nodules in the thyroid gland. CT examination can mostly make a clear diagnosis of multinodular goiter in the neck extending into the chest and can differentiate it from other mediastinal tumors. (5) Most Graves' disease is accompanied by hyperthyroidism, goiter, and proptosis. In a few cases, there is no clinical manifestation of hyperthyroidism, but only proptosis, which is called ophthalmic Graves' disease. In this case, CT examination can not only differentiate the disease from other causes of proptosis, but can also refer the patient to further clinical examination, such as TSH excitation test, which may reveal abnormalities.