Hand numbness may be related to cervical spine disease, cerebrovascular disease, poor local blood circulation. 1. Cervical spine disease: prolonged low head work or keep a posture for a long time to work or play cell phone, can cause cervical spondylosis, cervical nerve root stimulation can appear after the symptoms of hand numbness, can be accompanied by neck discomfort, dizziness and other symptoms. 2. Cerebrovascular disease: people who usually suffer from high blood pressure, arterial plaque, aneurysm may be induced by staying up all night to suffer from cerebrovascular disease, such as cerebral infarction, cerebral hemorrhage and so on. The end of the limbs will have numbness and other discomforts due to insufficient blood supply. 3. Poor local blood circulation: when staying up late, keeping a posture for a long time, there can be symptoms of poor local blood circulation in the limbs, and temporary numbness of the limbs can occur. Hand numbness after staying up late, if the activity improves, generally do not need treatment; if the symptoms of hand numbness often occur, you need to go to the hospital, further examination to confirm the diagnosis, clear cause and then treatment.