The following drugs can be used to relieve painful osteophytes: 1. Non-steroidal anti-inflammatory and analgesic drugs, such as Furtalin enteric capsules, Celecoxib, Clonoxicam and other drugs can effectively reduce local inflammation, reduce inflammatory edema and reduce pain. 2. Local closed injections can be performed, commonly used drugs are prednisolone acetate injection and lidocaine hydrochloride injection mixed with local painful points. 3.If the osteophytes occur in the joint, you can inject compound betamethasone injection into the joint, also known as Depo-Provera injection, to effectively relieve the inflammation in the joint, which can also reduce the pain. 4.You can take oral Chinese medicine that activates blood circulation and relieves blood stasis, soothes the tendons and improves collaterals, such as Guilong Tendon and Bone Capsules, and sodium heptaerythroside tablets, which can 5. You can take oral glucosamine hydrochloride capsules to effectively inhibit the degeneration of cartilage and prevent osteophytes and calcification.