Clinically used surgical anesthetics can be divided into two categories, one is local anesthetics, the other is general anesthetics, and in the process of surgery will also be used with muscle relaxants and analgesics. 1. Local anesthetics can be divided into esters and amides. The commonly used ester local anesthetics include procaine, bupivacaine and so on. Amide local anesthetics include lidocaine, bupivacaine, ropivacaine and so on. It should be noted that allergy should be prohibited such drugs. 2. General anesthetics can be divided into inhalation anesthetics and intravenous anesthetics according to the route of administration and mechanism of action. Inhalation anesthetics refers to the drugs that enter the human body through the respiratory tract and produce the effect of general anesthesia. Inhalation anesthetics commonly used in clinical practice include nitrous oxide and sevoflurane. Intravenous anesthetics refer to drugs that enter the body through intravenous injection and act on the central nervous system through blood circulation to produce general anesthesia. Commonly used intravenous anesthetics are ketamine, etomidate, propofol, midazolam and so on. 3. In addition, muscle relaxants and narcotic analgesics are also indispensable drugs in general anesthesia. Although the muscarinic drug does not produce anesthesia, but by blocking nerve-muscle conduction to make the skeletal muscle relaxation, so that the operation is easy to operate, but also to avoid the harm caused by deep anesthesia. The commonly used muscarinic drugs are succinylcholine, vecuronium bromide, rocuronium bromide and so on. Commonly used narcotic analgesics are fentanyl, remifentanil, sufentanil and so on. Surgical anesthesia drugs are a special class of drugs that can cause adverse reactions such as allergy, respiratory depression, and decreased blood pressure, and should be used strictly under the supervision of an anesthesiologist.