The common clinical causes of large stomach pain are mainly the following: i. Obese patients will suffer from hyperlipidemic pancreatitis due to elevated blood lipids, which will result in a large amount of pancreatic fluid seeping into the abdominal cavity and causing severe abdominal pain. Patients will be accompanied by nausea, vomiting, chills, high fever and other symptoms of systemic toxicity, at this time need to strengthen anti-infection, analgesia and rehydration support treatment. Second, patients with large belly who are accompanied by intestinal tumor lesions will cause the manifestation of intestinal obstruction, abdominal pain, abdominal distension, anal exhaustion and defecation stop. Patients can improve abdominal CT and colonoscopy to clarify the nature of the lesion. Third, patients with physical obesity will also experience severe pain in the stomach because of perforation of the digestive tract and penetration of corrosive fluid in the gastrointestinal tract into the tissue interstices. After the nature of the lesion is clarified by perfecting abdominal X-ray examination, surgery can be performed as soon as possible to repair the perforation and relieve the symptoms of the abdomen more quickly.