After various antibiotic poisoning, there will be different degrees of symptoms, such as gastrointestinal symptoms, such as nausea, vomiting, loss of appetite or abdominal pain, diarrhea and so on. Tetracycline and erythromycin, chloramphenicol, etc. are more prominent, while penicillins, especially penicillin G, when the systemic dose of the drug is relatively large, or when the intravenous infusion is relatively rapid, it will cause headache, vomiting, nuchal rigidity and so on. Gentamicin and kanamycin, or streptomycin, can cause vertigo, tinnitus, hearing loss, and can lead to permanent deafness. Streptomycin injections can cause numbness around the mouth and lips, as well as the hands and feet, headache, tinnitus, and in severe cases, vomiting, profuse sweating, flushing, difficulty breathing, or unconsciousness. Chloramphenicol can cause granulocyte and thrombocytopenia aplastic anemia and so on. Rifampicin, tetracycline and erythromycin can cause liver damage. All types of antibiotics can cause allergic reactions in sensitized individuals, such as fever, itchy skin, rash, hives, or in severe cases, hypotensive shock, etc. Penicillin is the most likely to cause allergic reactions, and penicillin is the most likely to cause allergic reactions. Penicillin is most likely to cause anaphylactic shock, and some antibiotics can cause elevated ghrelin and bilirubin, or oliguria, proteinuria, and so on.