How does the immune system fight the flu virus?

  A part of the flu virus agents, skilled hitchhikers headed for your nose, a science fiction blockbuster about the virus and the battle of cells is about to be staged in your body.  The season changes, you can hardly catch a bus, the door closes, the car is crowded, the car starts, the car stops abruptly, at that moment, a man with a mask dropped his mask due to inertia, and sent a sneeze in your direction, the air blowing from his mouth to you is 40 miles per hour, equivalent to a force 8 wind, part of the flu virus agents skillfully hitchhiking to your nose The ride is on.  Now a science fiction movie about a virus vs. a cell war has begun inside you.  The stinging virus agents first land in the thick nasal hair bush, unfortunately, some of your comrades are decapitated by your thick and mucousy nasal hair, martyred! The rest smoothly invade deep into the nasal cavity with their breath. Their only task is to reproduce themselves as much as they can, but they must invade some kind of cell in the throat of their destination in order to carry out their task, and finally, with the help of breathing, they cross your curved and complicated nasal passage, enter the throat, and pass bravely through the thick mucus and approach the target cell.  The spines on the surface of the virus can be disguised as simulated proteins, enough to deceive the cell into thinking that the virus is a protein, one of its own, and these spines are the IDs forged by the agents – there is nothing innovative about this, as in most Hollywood secret agent blockbusters, and again, after entering the cell, smoothly to the cell’s control center, the main computer The cell nucleus is implanted with a hacker program, a small piece of DNA, which completely controls the cell’s control system and uses the cell’s working methods to create the raw materials needed to replicate itself.  Just like the endless desire of human beings, these virus agents were soon not satisfied with just invading one cell and began to invade surrounding cells. 2 hours later, they had invaded 5,000 cells, the war was over and the immune system belonging to you began the first wave of counterattack.  The front line troops called natural killer cells (NK cells), began patrolling, looking for and trying to destroy the virus hidden inside the cells, but because their equipment is not as sophisticated and advanced, they could not enter the interior of the cells and simply sprayed toxins en masse, killing the virus while also allowing their own cells to be buried with them. Even so, it is still not enough to suppress the virus, their human tactics are so successful that the speed of giving birth to children far exceeds the killing power of NK cells. At this point 12 hours have passed since the virus agents began to invade your body and more cells have been infected.  The damage is severe and the cellular debris carcasses keep piling up, and if you don’t get these debris out in time, you are likely to have trouble breathing. At this point, macrophage units make their appearance, and one of the weapons of these big guys is to eat, trying to swallow the cellular debris, and the debris that is not swallowed is cleared out by the ciliary system. Due to the large number of throat cells buried with you, your throat starts to become red and sore. These symptoms are not directly caused by the virus, but appear due to the defense of the immune system – as long as there is a war, no matter what kind of war, it is always the civilian population that suffers.  Of course, as eaters, macrophages do not just know how to eat, they can also release a chemical called interleukins, calling for reinforcements to join the battlefield, the war situation is not favorable, they began to throw flares. These interleukins themselves both pyrogenic function, that is, will make your body temperature increase, because usually your temperature due to the role of the hypothalamus thermostat, the temperature will be maintained at about 37 degrees Celsius, and this is precisely the most comfortable temperature of the flu virus agents, can recklessly replicate themselves, the body temperature of the body can slow down the replication of the virus to some extent.  Then you feel cold and your body starts to shiver in order to generate more heat to increase your body temperature and slow down the replication rate of the virus, yes, you have a fever, but this is not a bad thing at first, at this point, if you use antipyretic drugs too early, it will allow the virus agents to revive. Interleukins also sensitize the nerves and the slightest movement can cause pain at this point. Don’t complain about your body, it is trying to remind you to move slowly in this way because your body needs all the energy it can get to defeat the virus. It seems that sometimes things that seem like they might hurt us are not always negative, and it’s not a blessing when you lose a horse.  Another benefit of increased body temperature is that other activities in the body begin to accelerate, allowing the immune system to produce more new immune cells faster and hair and nail growth to accelerate by 20%. The blood vessels in your brain dilate, which can give you a headache, and the dilated blood vessels in your nose can give you a stuffy nose, at which point you feel very uncomfortable, but the immune system will make it even harder until the virus is completely destroyed.  The war goes into a white heat as more natural killer cells arrive in the throat, while millions of viruses are still mushrooming. To win a war, brute force is definitely not enough, so the think tank within the immune system, the central intelligence analysts, a class of immune cells called dendritic cells came on the scene, they began to collect pieces of the virus, analyze the spikes carried on the surface of the virus, looking for a breakthrough that can completely defeat the virus.  Not to be outdone, they collected the key data, carrying a viral spike, and set out for a mysterious place where two of the most powerful soldiers of the immune system reside, B lymphocytes and T lymphocytes, a mysterious place called the lymph nodes, which are found in many parts of your body and are always on standby. After receiving the data that the dendritic cells have worked so hard to deliver, the B and T lymphocytes immediately respond by replicating themselves at a rate of thousands per hour, and your lymph nodes begin to swell. The T lymphocytes are able to pinpoint the virus and kill the cells that are filled with the virus. At this point you start coughing, which is a very good protective mechanism to get rid of all the potentially life-threatening substances in the airways, and the ciliary system that used to remove cellular debris is damaged by the war, so the body uses coughing to perform this function.  The B lymphocytes’ trick is to produce and release millions of antibodies against the viral spikes, locking them firmly so that they cannot infect other cells. The T and B lymphocytes divide their work, the former taking care of the virus inside the cell, the latter killing the virus that is free outside the cell, and the battle is won.  The end of the movie: new laryngeal cells start to grow, and you return to your old vigor. The lymphocytes do not take pride in their work, most of them are finished, and as the sun sets, they are like cowboys, leaving you with a fading back. A small number of them are left to patrol your body as memory cells, so that when the same virus invades again, they can directly start the ace T,B lymphocytes to kill the virus without causing any discomfort to your body, but the flu viruses have a trick up their sleeve, they will mutate so that the next time the flu hits, you will still get the flu, after all, Hollywood directors always like to make sequels.