Recently, 2 elderly people came to consult the vitamin B2 diet, one showed frequent diarrhea and had stomatitis, and the other showed dry mucous membranes and stomatitis. Both of them used to be scientific and technological backbone, and they like to get to the bottom of things, and they are serious people; the first one is a bit impatient, but very quick to do things; the second one is a bit forceful, and they want to take charge of everything at home, and they get angry when their family members don’t listen. According to the general process, I first look at their past laboratory results and medical records, and then investigate their eating habits, and then give dietary treatment plans and precautions. Finally, I discussed with these two elderly people about the relationship between personality and health, and how a strong woman’s retirement life should be arranged. In fact, they know that they are impatient, not used to seeing many things, often anxious and angry, I told them “are more than 70 years old, within the ability of things can be done, but outside the ability of things should not be forced, if forced not only can not solve the problem, but also add interpersonal worries, affect health, this is to lose a wife and a broken army ah “. In fact, many diseases if you can have a calm mind and relaxed character, the treatment will be twice as good with half the effort. Depression, tension, irritability and anger can affect the digestion and absorption of nutrients and aggravate the development of the disease, especially mucous membrane diseases, which have a lot to do with mood. I hope similar elderly people can pay attention to the impact of mood on their health, the following with you to learn about VB2: 1, what is VB2? VB2 is also called riboflavin, chemical formula C17H20N4O6, molecular weight 376.37, is slightly soluble in water water-soluble vitamin (27.5 ℃, solubility 12mg/100mL), acid resistance, oxidation resistance, heat resistance, easily soluble in Alkaline solution, alkali and light can cause its irreversible destruction 2, the role of VB2? VB2 participates in redox reactions in the form of flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), and acts as a cofactor for redox enzymes and plays a role in hydrogen delivery. It is mainly involved in the oxidative metabolism of sugar, protein and lipids, the conversion of purine bases into uric acid, the hydroxylation of aromatic compounds, the synthesis of certain hormones, the transport, storage and mobilization of iron, the metabolism of folic acid (VB9), pyridoxine (VB6), niacin (VB3/Nicotinic acid/vitamin PP/anti-mangeogenic), as well as antioxidant, eye fatigue reduction, swelling and diuretic, tumor prevention, reduction of cardiovascular and cerebrovascular diseases It also has the functions of antioxidant, eye fatigue reduction, swelling and diuretic, tumor prevention, cardiovascular disease reduction, migraine prevention and control, and sex quality improvement. 3, VB2 in vivo metabolic process? Most of the dietary VB2 exists in the form of FMN and FAD coenzyme combined with protein. After entering the stomach, under the action of gastric acid, it is separated from protein and transformed into free VB2 in the upper gastrointestinal tract before being absorbed in the upper part of the small intestine. At higher intakes, the liver and kidney concentrations are higher, but the body’s ability to store VB2 is limited and it is excreted in free form by the urinary system when the renal threshold is exceeded, so it must be supplied daily by the diet. 4.Symptoms or diseases of VB2 deficiency? Mild deficiency has no obvious symptoms, but severe deficiency may cause the following symptoms: 1) Oral-genital syndrome: inflammation and dysfunction of the mouth, eyes and external genital area, such as stomatitis, lip infection, tongue infection, conjunctivitis and scrotum infection, etc.; 2) Sexual frigidity or loss of libido: in the absence of VB2, the mucous membrane in the human cavity becomes thinner, the mucous layer is damaged and the microvasculature is broken. 3) Long-term deficiency of VB2 in children can lead to developmental delay with mild to moderate iron deficiency anemia; 4) Often accompanied by other B vitamin deficiency symptoms. Due to the relatively low solubility and limited intestinal absorption, overdose toxicity is rare. 5. What are the common causes of VB2 deficiency? Inadequate intake, alcohol abuse, drug effects (such as antipsychotic promethazine, anticancer drug Adriamycin, antimalarial drug Adipine, etc.) 6.How to diagnose VB2 deficiency? VB2 deficiency is often accompanied by other B vitamin deficiencies, and there is no unified diagnostic standard. Urinary VB2 excretion is often used as a diagnostic basis, such as urinary riboflavin/creatinine measurement (<27μg/g creatinine is deficiency, 27-79μg/g creatinine is deficiency), urinary excretion load test (after oral administration of riboflavin 5mg, 4h urine is collected to measure the excretion. Those with <400μg/4h urine are deficient, those with 400~799μg/4h urine are deficient), determination of glutathione reductase (EGR) activity coefficient of red blood cells (those with AC value >1.20 are deficient), etc. In the absence of experimental diagnostic conditions in primary hospitals, VB2 can be tried first for suspected cases, and those with effective results can confirm the diagnosis. 7.How to treat VB2 deficiency? (1) Eat more food rich in VB2; (2) Take VB2 tablets in appropriate amount when symptoms are serious, the absorption effect is poor on an empty stomach, take them when eating or immediately after meals, and stop taking them when symptoms improve. (3) VB2 works best in synergy with VB6 or vitamin B complex. 8.What are the high-risk groups for VB2 deficiency? VB2 deficiency is more common, and children who grow faster are more likely to be deficient in VB2. In addition, pregnant and lactating women, people who do not eat lean meat and dairy products, vegetarians, people with chronic mental stress, people with high fever, burns, smokers, people with chronic gastrointestinal diseases, people who repeatedly heat food or need to control the amount of diet for other reasons are more likely to have VB2 deficiency. 9, dietary supplementation of VB2? The body’s storage of VB2 is limited and needs to be supplied by diet every day. VB2 is widely found in various types of food, such as yeast, animal liver, kidney, heart, eggs, milk, soybeans, green leafy vegetables, etc. The content of animal products is higher than that of plant foods. Therefore, you should make full use of animal foods such as animal liver, eggs and milk, eat more fresh green leafy vegetables, various legumes and coarse grains, reduce the storage time of food and cook scientifically to minimize the loss of VB2 (adding sodium bicarbonate when cooking to keep vegetables green will destroy their biological activity). For adults, 1.4mg/d for men and 1.2mg/d for women are recommended. 10.Other uses of VB2? As a food additive, it is commonly used in wheat flour, dairy products, soy sauce, rice, bread, cookies, chocolate, sauces, etc. It is also sometimes used as a color.