Premature ejaculation has a high incidence in male sexual dysfunction, and the diagnosis of premature ejaculation is mainly based on clinical manifestations. Early patients ejaculate too quickly during sex, usually less than 2 minutes of sex after the penis is inserted into the vagina, and the course of the disease can be diagnosed as premature ejaculation if it reaches more than 6 months. Patients with severe premature ejaculation may ejaculate just after the penis has been erected or just after the penis has touched the vulva of the woman. Due to the rapid ejaculation, the quality of men’s sexual life is seriously affected, so it needs to be actively treated to improve the situation. At present, the treatment of premature ejaculation can be achieved by mastering sexual skills, and can also be treated with oral medication or topical medication. Commonly used oral drugs are dapoxetine hydrochloride. Topical drugs are mainly local anesthesia drugs, which can be applied to the glans before sex to reduce sensitivity, thus prolonging the time and achieving the purpose of treating premature ejaculation.