Muscle throbbing from time to time in various parts of the body, i.e. involuntary muscle movement, is usually caused by physiological factors such as high psychological stress and overwork, so proper rest is needed. Although the existence of amyotrophic lateral sclerosis, neuromuscular ankylosis and other pathologic factors is less likely, but if the patient is accompanied by other symptoms, it is recommended to consult a doctor in a timely manner to clarify the diagnosis and comply with the doctor’s instructions for treatment. Physiological factors: 1, psychological stress: usually due to work, life and other factors lead to psychological stress, so the body and mind will be in a state of fatigue, at this time, the muscles will also appear related reactions, such as jumping from time to time, fatigue and so on. Usually through rest, listen to light music to relieve pressure, the symptoms can be improved accordingly; 2, too tired: such as often stay up late, engaged in heavy physical labor, as well as strenuous exercise, etc., may lead to muscle tension and fatigue, thus making the muscles to appear involuntary phenomenon, the patient may be appropriate to give hot compresses, local massage and other ways to improve. Second, pathological factors: 1, amyotrophic lateral sclerosis: that is, acromegaly, is a chronic neurological disease, early can appear muscle beam tremor, that is, the whole body of all parts of the muscle from time to time jumping, but the late stage of muscle atrophy, skeletal muscle weakness and other symptoms can gradually appear. There is no specific drug for treatment, but drugs such as edaravone injection can be given to improve the neurological symptoms; 2. Neurogenic muscle ankylosis: it is a rare peripheral nerve excitability clinical syndrome of peripheral nerve origin, with insidious onset and slow progression in children and adolescents. This disease is mainly manifested as muscle twitching, muscle spasm, muscle stiffness and excessive sweating, etc. Clinical diagnosis can usually be made by electromyography, etc. After diagnosis, carbamazepine tablets and other medicines can be used for treatment according to the doctor’s instructions.