In clinical work. In the clinical work, the severity of the disease cannot be judged only by the minor triple positive or major triple positive of the hepatitis B pentameter, but should be combined with the liver function, hepatitis B virus DNA quantification, liver ultrasound and other specific conditions to judge the patient’s condition. Therefore, it is very important for hepatitis B patients to have a regular review, which can be done once every six months, and if there is any discomfort, it should be done at any time. The items of review mainly include liver function, quantification of hepatitis B five items, quantification of hepatitis B virus DNA, as well as alpha-fetoprotein, liver ultrasound, liver elasticity measurement and so on. If the indications for antiviral treatment are met, antiviral treatment should be carried out in a timely manner, so as to suppress viral replication and avoid disease progression. If antiviral treatment is not given in time, the condition can gradually progress to liver fibrosis, cirrhosis, or even liver cancer.