Laser spot removal belongs to the common physical treatment measures for removing spots in clinic, but it also has certain side effects, such as pain, blisters, hyperpigmentation, scarring and so on. 1. Pain: laser spot removal is through the selective photothermal effect of laser, smashing melanin particles and accelerating their metabolism and absorption. The process of phototherapy will be irritating to the local skin nerves, so there will be different degrees of pain symptoms. 2. Blisters: The photothermal effect of laser will lead to localized thermal burns if the energy or mode is not properly selected, causing swelling of tissue exudate, so there may be blisters at the treatment site. 3. Hyperpigmentation: laser spot removal has some damage to the local skin barrier, if the repair process of infection or not pay attention to sunscreen, it will cause different degrees of hyperpigmentation. 4. Scar: excessive laser energy, infection during the healing process or improper treatment of thermal burns may result in the formation of scar. Laser spot removal should go to a regular hospital for treatment, and if side effects occur after treatment, you should actively seek medical advice and follow the doctor’s instructions.